产品货号：
Z11932
中文名称：
BCL2L13抗体
英文名称：
Anti-BCL2L13 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCL2L13 Antibody |
| 指标别名 | BCL2L13;MIL1;Protein Mil1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | BCL2L13 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Bcl-rambo antibody was raised against a 15 amino acid synthetic peptide from near the center of human Bcl-rambo.The immunogen is located within amino acids 280 - 330 of Bcl-rambo. |
| 计算分子量 | 53kDa |
| 成分 | Bcl-rambo Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bcl-rambo Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells.Disruption of this process has been implicated in a variety of diseases such as cancer.Members of the Bcl-2 family are known to be critical regulators of this process.These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains.A novel,widely expressed member termed Bcl-rambo was recently identified.This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP,cIAP1,and cIAP2.Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs,but unlike Bcl-2,the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion.This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions,suggesting that Bcl-rambo may be important other pro-apoptotic pathways. |
| Uniprot ID | Q9BXK5 |
| 基因名全称 | BCL2-like 13 (apoptosis facilitator) |
| 蛋白名全称 | BCL2-like 13 (apoptosis facilitator) |
| 推荐稀释比 | Bcl-rambo antibody can be used for the detection of Bcl-rambo by Western blot at 2 and 4μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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